Bynes recently pleaded not guilty in her suspended driving license case as well as two hit-and-run driving charges.
The actress worked with Jonathan on the popular WB series What I Like About You, in which they played best friends for four seasons.
Jonathan has now told TMZ that Bynes should not be driving at this point in her life.
"The only thing I would say to her is 'You got enough money. Get a chauffeur to take you everywhere'," he said.
The actor also insisted that he has no ill will towards Bynes and wishes her well.
Jonathan commented: "Everybody makes mistakes. We're all human."
Bynes most recently threatened to sue In Touch Weekly over an article claiming that she walked around nude in a tanning salon.