Seven years on, a marriage and baby later, among other life and career monuments, the best-selling girl pop group Destiny's Child have returned with a new album.
Between then and now, the popstar trio split and did their own thang. They branched out into Hollywood movies, Broadway productions and pinnacle British reality shows.
In celebration of their set-to-be-mighty return, here are ten facts about the group.
1. Beyoncé Giselle Knowles-Carter, Kelendria "Kelly" Rowland and Tenitra Michelle Williams make up the renowned trio. Calling themselves Destiny's Child from 1996, Beyoncé's father Mathew Knowles, who was also their manager, had the girls practising killer dance moves and vocal harmonies at his family crib in Houston, Texas.
2. Remember Letoya Lucket? LaTavia Robertson? Farrah Franklin? All previous Destiny's Child ladies. The girls began as a group of four with Lucket and LaTavia joining Beyoncé and Rowland, swiftly to be replaced with Williams and Franklin. But six months into Franklin's Destiny's Child lifestyle she was given the boot. She reportedly brutally learned of her dismissal via an MTV News bulletin.
3. Between 1997 and 2005, Destiny's Child reigned as the world's top-selling female vocal group achieving combined sales of more than 60 million records.
4. After their second comeback in 2004 with the album Destiny Fulfilled, the DC girls toured the world. As they were sponsored by McDonald's the tour name adopted the fast food parlour's slogan and was labelled 'Destiny Fulfilled... and Lovin it'.
5. The girls' long reign as R&B royalty has become inspiration to current celebrities. Girls Aloud listen to Destiny's Child before their own gigs, Katy B has labelled them as her inspiration, along with Zane Lowe's Sound of 2013 sisters Haim.
6. The name "Destiny's Child" is derived from a passage in the Book of Isaiah. The Knowles are passionately Christian and Beyoncé's mother suggested the name when "Destiny" had been taken.
7. The girls have stretched their careers into different industries. For example, 2010 saw Beyoncé and her mother Tina open the Beyoncé Cosmetology Centre at the Brooklyn Phoenix House as part of an adult career academy.
8. Kelly, Michelle and Beyoncé have taken up acting alongside their singing careers. Beyoncé has a string of Hollywood roles from her sassy Austin Powers character to Dreamgirls. Rowland made her debut in 2003 with Freddy vs Jason and Williams has had flourishing roles in Broadway and the West End, currently stepping up as Sandra in the Tony-nominated musical Fela! in the US.
9. Rumours that the group will be performing at this Sunday's Super Bowl half-time performance were recently rubbished by Williams, who said: "I'm gonna be in the musical Fela! I hate to disappoint the people and tell them that it's not true."
However, Fela!'s official website reads: "PLEASE NOTE: Michelle Williams will not be appearing January 31st - 3rd."
10. And finally, the girls still have their fierce girl power spirit, with Williams telling MTV News after hearing the new album: "Beyoncé sent an email like, 'Man, we sound good together!' I'm like, 'Duh, that's what we do, boo! That's what we do!'"