Showbiz
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The Oscar-winning actress follows in the footsteps of Jessica Biel, Scarlett Johansson and Angelina Jolie to take top spot on the list.
Charlize appears in a photoshoot in November's edition, but revealed that her looks have not always helped her make the right decisions when it comes to her career.
Talking about the poorly-received film Reindeer Games, she said: "That was a bad, bad, bad movie. But even though the movie might suck, I got to work with John Frankenheimer.
"I wasn't lying to myself that's why I did it. I mean, he directed The Manchurian Candidate, which is like the movie of all movies."
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