Arquette is reportedly tired of Aniston's regular visits to their home since she broke up with Vince Vaughn and feels like he is "married to two women".
A source is quoted by TransWorldNews as saying: "Somewhat understandably, David’s now saying it’s him or Jennifer.
"He’s had enough and is drawing a line in the sand. He’s asking that Jennifer’s visits become less frequent and that there are no phone calls between midnight and 8 am.
"David is now telling friends that it feels like he is married to two women."