The singer has not been seen with celebrity hairdresser Ben Cooke, who was revealed to be her closest pal on last year's documentary Coming To America, for several months.
Now reports that the pair had a bust-up after Cooke accused Beckham of turning into a different person after she relocated to America with husband David last year.
A source said: "Ben doesn't speak to Victoria after he told her some home truths. Her friends think she's ignored them since her move to the US and they feel left behind.
"Victoria didn't like what she was hearing and got annoyed about it. Now she refuses to speak to Ben and doesn't really have anyone around apart from her mum and sister."
The Spice Girl has socialised with celebrities including Kate Beckinsale, Eva Longoria, Katie Holmes and Jennifer Lopez in LA.
Kerry Katona recently criticised her for appearing to have a new best friend every week.