The 'Oh My Goodness' singer took part in the 2010 edition of Soccer Aid alongside organiser Robbie Williams, with whom he duetted on The X Factor UK the previous year.
He told Daybreak: "I've been looking forward to it for the last two years, I last did it two years ago. It's an amazing week actually from the start - getting to the hotel on Tuesday, it's like a proper football team. We meet up, we train every day... there'll be a bit of banter in the changing room, it's a good week."
Discussing which stars he was most excited about meeting, he said: "Will Ferrell is the one I'm looking forward to the most, Woody Harrelson I think is there, there are so many, that's great. I don't know how they manage to pull the strings, but I think it's because it's such a great charity, UNICEF, I think the fact that everyone who's going to be involved with it will be just hoping to drive more people to donate and stuff like that.
"It's going to be a great night, on a personal level and also for the charity. It's great, do you know what I mean? I'm a massive football fan anyway as it is, so to actually get a chance to play at Old Trafford where some of the best players in the world have played is great."
Murs also spoke of the "great chance" he has been given to accompany One Direction on their upcoming US tour, saying: "I think I'm flying out on Monday morning, flying off to Canada to start the tour, it's going to be nuts.
"I've been over there the last couple of weeks. I've doing some writing sessions and getting involved in it but you know, I've always said before, going to America is great and it's a great chance for me, but there's no pressure in it, it's going to be good.
"The single is released on the 29th over there, which is quite close. But it works differently over there, it all works on airplay and it's driving it. But, I mean, it's going to be great to be on the tour with the [One Direction] boys as well."
The Xtra Factor co-host also insisted that he does not know who the fourth judge on the X Factor will be, stating: "Everyone's asking me! I genuinely don't know. We never find out. I know that they're sort of doing guest judges, I think that's going to be the idea for the auditions.
"I don't know, it's always changing. One minute I was told that yeah, it was definitely gonna be Dannii Minogue, then one minute I was told it was going to be someone else, so, it's always changing. It just depends on who Simon wants. We'll see. I'm sure it's going to be a great year this year. We've got a lot of competitions off other shows, so hopefully fingers crossed that we can pull it out of the bag."
Soccer Aid begins on Wednesday, May 23 at 10.35pm on ITV1. It will air for three nights ahead of its live match on Sunday, May 27 at 6pm.