The 'Read All About It' rapper teased that he would somehow get rid of the likes of Joey Essex, Lauren Goodger and Sam Faiers if he was Prime Minister for a day.
In a webchat hosted by The Sun, Green - real name Stephen Manderson - said: I'd put all of TOWIE in prison. Or maybe I'd kill them all and the country's IQ would rise... Only joking!"
Green also passed comment on the appearance of ex-TOWIE star Amy Childs at the BAFTAs this weekend, where she and cousin Harry Derbidge presented Celebrity Juice with the 'YouTube Audience Award', won by Essex the previous year.
"Amy Childs was at the BAFTAs presenting an award," he recalled. "Comedy's all about timing and there were some awkward sketches."
Green is currently dating Made In Chelsea star Millie Mackintosh.
Watch Professor Green in the video for 'Remedy' below: