The Irish actor landed the role of Dermot Macey on the show last autumn and he has appeared on screen since December.
However, speaking to Emmerdale's official website, Kelly confirmed that he will soon be bowing out from the programme.
He commented: "I have thoroughly enjoyed my time at Emmerdale and working within such a supportive and happy team, but travelling to Leeds each week from my home in Ireland has meant that work opportunities closer to home have proven too appealing to turn down."
Emmerdale's series producer Stuart Blackburn added: "Frank has been an asset to the cast and we wish him all the best for the future."
During his time in the village, Dermot frequently caused mischief by happily spending his son Declan (Jason Merrells)'s money at the pub. He also took a shine to show regular Pearl Ladderbanks (Meg Johnson).
Kirsty-Leigh Porter (Roz Fielding) and Suzanne Shaw (Eve Jenson) will also be seen leaving the show in the coming months.
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