Jai and brother Nikhil's mother Georgia will be played by The Bill's Trudie Goodwin, Holby Blue actor Bhasker Patel has been cast as her business-obsessed husband Rishi, while Where the Heart Is star Fiona Wade will take on the role of sister Priya, previously played by Effie Woods.
According to ITV, the Sharma family arrive in the Dales this autumn and will create waves over Jai's engagement to Charity Tate.
Goodwin said: "I'm absolutely thrilled to be playing Georgia in Emmerdale. She is a difficult-to-please woman who is set to make life difficult for Charity. I can't wait to start filming next week."
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Series producer Stuart Blackburn added: "I'm delighted to welcome Trudie, Bhasker and Fiona to the cast. There are plenty of trials and tribulations in store for the ever popular Sharma family."
Actress Effie Woods was cast as Emmerdale's original Priya in 2009, but soon left the show and has now been re-cast.