The actress signed up for the part of Anita Roy's (Saira Choudhry) long-lost mother Eva two months ago - her first major television role in six years.
Speaking on This Morning today, Murphy explained that she was initially wary of making a TV comeback because she knew it would mean less time to spend with her footballer husband Harry Kewell, who is based in Turkey due to his own career commitments.
She commented: "It is a long commute and it has been quite difficult. That's why when the phone call came up and I got the chance to appear on Hollyoaks, it was quite a difficult decision to make.
"Now that I have a job, I have to stay in England. But [Harry's] very supportive of what I do and he knew I wanted to go back to work."
The mother-of-three added that she relies on Skype to keep in touch with her partner, describing it as a "great invention".
Murphy's first episode of Hollyoaks airs on Channel 4 tonight.