The 29-year-old actor, who bowed out of the teen soap this year, refused to rule out a return for his bisexual alter ego Kris Fisher.
Speaking to PA, he said: "I've gone out with the door wide open so whether I'll come back is completely out there."
McCarthy added of his last scenes with co-star Kent Riley, who plays Zak Ramsey: "The amount of times we've been told off for laughing and giggling together means my last scene was never going to be emotional.
"It was shot in the same way we shot every other scene - just laughing and messing around, having a great time. We go out on a high."