Fans can expect three different couples to go ahead with plans to tie the knot in the coming weeks, but terrible danger lies ahead for all of them with a devastating mini-bus crash on the way.
Upcoming episodes see Tony Hutchinson (Nick Pickard) and Cindy Longford (Stephanie Waring) decide to combine their wedding celebrations with those of Ste Hay (Kieron Richardson) and Doug Carter (PJ Brennan), and so the foursome team up for a day which brings the whole village together.
At the same time, teenagers Ruby Button (Anna Shaffer) and Martin 'Jono' Johnson (Dylan Llewellyn) are planning to flee to Gretna Green to get married, having decided that it's time to reaffirm their love for each other before Jono leaves for the army.
The sixth formers all prepare to set off to Scotland together in a stolen mini-bus for Jono and Ruby's big moment, unaware that the brakes are faulty. To make matters worse, Bart McQueen (Jonny Clarke) and Esther Bloom (Jazmine Franks) are opposed to the nuptials and attempt to stop them all from leaving by chasing them on the road.
Amid the drama, the teens are startled when Ste's young daughter Leah suddenly gets in the way of the moving bus.
As driver Maddie Morrison swerves out of the way to avoid hitting Leah, the mini-bus hurtles straight into Tony, Cindy, Ste and Doug's wedding venue, mowing down everyone and everything in its path. The bus then blows up - a shocking accident tipped to change life in the village forever.
At least two characters are expected to be killed off in the momentous episodes, but their identities will be kept closely under wraps until transmission.
The disaster has also been tipped to "reveal secrets and lies that many had fought hard to keep hidden".
Hollyoaks kicks off the big week on Monday, November 12 at 6.30pm on Channel 4.