The actor, who plays Dennis Savage, revealed the news on his Twitter page on Thursday (April 24).
He told fans: "I want to tell you all from me that I'll be leaving Hollyoaks at the end of the year. It's an amazing place to work, and I'll miss it!"
Tracini, who joined Hollyoaks in late 2011, has not yet revealed any other information about his upcoming departure.
Dennis has been at the centre of the show's comedy storylines since joining the village two and a half years ago, with many of his early plots revolving around his crush on Leanne Holiday (Jessica Forrest).
The funnyman also featured in a more serious plotline late last year as Leanne tragically died just weeks after they finally got together.
Tracini has already confirmed his first post-Hollyoaks project as he has signed up for the role of Buttons in a Christmas production of Cinderella at the Wolverhampton Grand theatre.
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