The 26-year-old, who first appeared in the Channel 4 soap in 1997, will bow out in July in a shock dramatic exit surrounding his wedding to Steph Dean (Carley Stenson).
Darren Jon Jefferies has returned to filming with the Chester-based soap as Max's best friend O.B. for his final scenes.
O.B. makes a fleeting visit to Hollyoaks in a bid to persuade Max to join him on one last adventure to New York. Owing to his heart condition, however, Max finds himself in casualty with chest pains on the morning of his nuptials, while Niall Rafferty (Barry Sloane) has recently found himself a love rival in Max as he attempts to woo Steph away from her husband-to-be.
The real reason for his exit is being kept under wraps by the soap's bosses, but however he leaves the village, the repercussions are sure to impact his friends and family in a huge way, not least his little brother Tom (Ellis Hollins).
Speaking of his exit, Matt Littler said: "I feel that I have grown up on Hollyoaks over the past eleven years and I’m not only leaving behind friends but also family. I wouldn't change a second of my time at Hollyoaks and working with Darren Jon Jefferies has been amazing – every second of it! I'd just like to thank everyone who has made my life at Hollyoaks a very happy one."
Producer Bryan Kirkwood added: "Matt, together with Darren Jon Jefferies have created a partnership in Max and O.B. that has been at the heart of Hollyoaks success for the last eleven years. Matt is a talented directed as well as a successful actor and although Max's exit marks the end of an era on screen, Matt's not going too far as he will be directing a few episodes of Hollyoaks in the not too distant future."
Littler films his final scenes at Lime Pictures, the home of Hollyoaks, next week and the scenes are due to air on Friday, June 27 at 6.30pm on Channel 4.
Last month, it was announced that Kev Sacre - Hollyoaks' Jake Dean - would also be leaving the soap after six years in the role.