Later this year, viewers will see Paul Robinson's (Stefan Dennis) life left hanging in the balance when he is pushed from the mezzanine level of Lassiters in a shock attempted murder plot.
The sinister event will be screened in a special week of episodes which are due to air in the UK from October 11. In the run-up to episode 6,000 - airing on October 15 - a new suspect will be revealed each day, as possible motives of Paul's many foes and the events leading up to his fall are explored.
A statement released by Neighbours' British broadcaster Five said: "With so many enemies, it will be hard to narrow down who had the motive to harm him. Who pushed P.R?"
The show's executive producer Susan Bower previously hinted at the forthcoming plot last month, saying: "Paul Robinson, or P.R as we like to call him, has been up to his usual tricks over the past few weeks and everyone on Ramsay Street is becoming really sick of him. What will they do about it?"
Neighbours' 6,000th episode - which airs in Australia later this month - will also see on-off lovers Ringo Brown (Sam Clark) and Donna Freedman (Margot Robbie) tie the knot.