The Ramsay Street favourite, who was diagnosed with the disease back in 2007, refuses help from estranged husband Karl but struggles to do jobs around the house.
Susan, played by Jackie Woodburne, will turn to Dr Rhys Lawson, who understands her situation and agrees to help her maintain a level of independence.
"Susan always had Karl to keep an eye on her in case she suffered an episode," an insider said to the Daily Star.
"Viewers will see her struggle to deal with even the simplest domestic chores.
"She always knew it was going to be hard living alone, but Karl is the last person she wants to turn to. She doesn't want to admit she needs him but she does. In the end she confides in Dr Rhys."
Susan's battle will air on Channel 5 in the UK this summer.