Actress Jiordan Tolli recently reprised the role for a special episode, which will air in October on Australian screens and a month later in the UK.
Tolli joined Neighbours when she was a baby and played the part of Lolly for seven years, before leaving the soap in 2001 to concentrate on her education.
More recently, she has been competing as a solo singer on the Australian version of The X Factor.
Speaking of her return, Tolli commented: "I spent a big part of my childhood on the show so it felt very comfortable coming back to the studios to film the episode."
Reflecting on her original stint, she added: "I had a wonderful time on the show and just remember it always being fun, however after seven years, my parents felt it was time for me to go to school full-time like regular kids which was the right decision."
Lolly's return storyline will see her arrive on Ramsay Street to celebrate Lou's 70th birthday.
Tom Oliver, who plays Lou, was responsible for creating the character of Lolly in the '90s.
Oliver explained: "At the time, Lou was married to Cheryl and I put to the writers the idea of a woman having a child later in life and some of the risks involved. The result was this lovely young lady.
"It's wonderful to have her back on set and she is almost taller than me, so it's lucky I don't have to carry her around like I did in the early days!"
Adelaide Kane was the last actress to be seen on screen as Lolly, appearing for a few months in 2007.
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