Fans will soon see the actress's alter ego Leah Patterson-Baker feeling too scared to leave her home as she struggles to cope with the trauma of Summer Bay's recent race riot and subsequent Diner fire.
Discussing her character's new plotline, Nicodemou told TV Week: "It was interesting because I haven't done anything like this before. On a personal level, I'm glad the story happened - and it's great that Home and Away is dealing with racism."
On what viewers can expect from the story, she explained: "The anxiety makes [Leah] question her job at the Diner and a whole range of stuff. Basically, she doesn't want to leave her house and her friends are really worried about her.
"Audiences will see a really broken Leah. She's usually full of heart and spirit. She's always been a real fighter, but everything gets stripped away from her and she can't even deal with looking after her son VJ."
Nicodemou recently said that she will have a new romance storyline this year.