The Summer Bay pair have called time on their relationship after less than three months, according to Australia's Daily Telegraph.
Whitehead, who plays Liam Murphy on the show, confirmed that he and Weaving were an off-screen item in June.
He said at the time: "It's only new but it's going really well."
The actor is said to have been spotted with a new girlfriend in Surry Hills last month.
Weaving, who plays Indigo Walker, has also apparently been seen with a new partner.
Whitehead's most notable previous relationship was with actress Lisa Gormley.