The actress filmed her final scenes for the BBC One drama in the summer, and viewers will see Cherry bow out later this month.
Abelson made the decision to leave Doctors earlier this year in order to pursue new acting opportunities.
While firm details of her exit have yet to be revealed, viewers can expect Cherry's marital problems with Jimmi (Adrian Lewis Morgan) to come to a head before she goes.
Abelson told Digital Spy of her Doctors departure: "It's very sad. I was there for three and a half years, I had an amazing time and it was a great experience. I learned lots and worked with some amazing people, but I felt that the time had come to move on and see what else was out there.
"Overall I miss the people a lot, and when I look back on my time on Doctors, it was fantastic. So it is sad, but it's also exciting to think what the next chapter in my life might be."
Cherry slept with colleague Daniel Granger (Matthew Chambers) earlier this year and has since been desperate to ensure that their secret is not exposed.
Doctors airs weekdays at 1.45pm on BBC One.
Check back on Digital Spy next week for a full interview with Sophie about her Doctors exit.