Digital Spy can confirm that Butterflies actress Wendy Craig appears in the episode airing on Tuesday, February 26 - taking on the part of Edith Jessop.
Edith is the overprotective mother of Heston Carter's friend Rory. She is determined to break up her son's potential relationship, but will she succeed?
Meanwhile, The Kumars at No. 42 stars Indira Joshi and Vincent Ebrahim have also recently been filming with the BBC One daytime drama.
The pair will be seen in a story involving a couple with marriage problems, which are fuelled when Joshi's character hears her husband calling out another woman's name in his sleep.
Viewers will see that there could be an innocent explanation for this suspicious behaviour, but can Dr Kevin Tyler (Simon Rivers) help the pair to open up again?
Doctors airs weekdays at 1.45pm on BBC One.