The BBC One serial again collected the major award it won last year, while the show picked up seven awards in total at the ceremony at One Marylebone in London today (September 24).
> Inside Soap Awards 2012: The Full Winners' List
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Gillian Wright was named 'Best Actress' for her performance as Jean Slater, while Hetti Bywater's Lucy Beale was 'Best Newcomer'.
Charlie Brooks's Janine Butcher was named 'Best Bitch' and David Witts's Joey Branning won 'Sexiest Male'.
Ricky Norwood and Tameka Empson were named 'Funniest Male' and 'Funniest Female' for their roles as Arthur Chubb and Kim Fox respectively.
Despite leading the shortlist with 16 nods, Coronation Street picked up just three prizes.
Alex Bain was named 'Best Young Actor' for his performance as Simon Barlow, while Michelle Keegan won the double of 'Sexiest Female' and 'Best-Dressed Soap Star'.
Also winning a brace of prizes was Hollyoaks star Emmett J Scanlan (Brendan Brady), who was named 'Best Actor' and 'Best Bad Boy'.
Neighbours was the big daytime winner, picking up the 'Best Daytime Soap' gong, while Ryan Moloney was named 'Best Daytime Star'.
The 'Best Drama' prize went to Waterloo Road.