Kara and James decided to end their 18-month relationship this week. The pair realised that they had drifted apart after spending much less time with each other this year.
Alexandrou toured with the Royal Shakespeare Company after quitting his role as Martin Fowler on the soap in February.
Meanwhile, Tointon's EastEnders commitments have been bigger, because her character Dawn Swann has been at the centre of some of the show's biggest storylines.
A spokesman told the Sunday Mirror: "It is all very amicable."
More: Soaps, EastEnders
Soap Scoop
Corrie Carla, Enders romance, 'Oaks kissWe present the latest spoilers and pictures from the UK soaps.
Soaps Interviews
Neighbours star teases Rhys's futureBen Barber chats to us about his latest Neighbours plot and more.
Soap Ratings
Helen Flanagan's Corrie exit draws 9.3mThe young actress brings in more than 9.2m for both episodes in the double bill.
Reality Bites
Does Simon Cowell have new SuBo?: VideoWatch a clip of Jonathan Antoine, who is tipped for success on BGT.
