The 90-year-old actress, who joined the ITV soap in 1969, told The Mirror that she won't quit her role as Betty Williams.
"If I retire, I'll be dead in six months with boredom," she said. "I love working. I can't retire, I won't retire - I never ever will. I don't believe in it. I think you're foolish if you give up a job you love."
She continued: "I've got a lot of friends who've got to 65 and said, 'Right, well we've done our bit now, we'll pack it in.' And I've watched them grow old - you can see them suddenly getting old. You mustn't do that. It's working so hard that keeps me young."
Williams insisted that she won't let health problems get in her way.
"I won't give in. I've had operations for two new knees earlier this year and just a few months ago I had pneumonia," she said. "Even though I was ill, I always knew I'd come back to the Street.
"We all have terrible times at some time or other, but I tell all my friends - you mustn't give in. You've got to have an enthusiasm for life."
She added: "When I was young, I didn't even think I'd be alive at 90, let along working."