With the show's much-anticipated milestone now just weeks away, the programme has today announced details of the Coronation Street 50th Anniversary Appeal, which will benefit Cancer Research UK, the NSPCC and The Christie cancer centre in Manchester.
Over the next few months, the drama's cast will be taking part in fundraising activities both on and off air, while also calling for donations to be made via an official website for the appeal.
Pictured: Cast members Michelle Keegan (Tina McIntyre), Debbie Rush (Anna Windass) and Antony Cotton (Sean Tully) promote the appeal.
Speaking of the charity project, Coronation Street's executive producer Kieran Roberts commented: "During 50 years of storylines, Coronation Street has covered an enormous range of social issues. As part of our 50th anniversary activities, the cast and crew felt it was important to give something back in the form of an official appeal.
"The three charities nominated carry out extraordinary work and we want to support them as much as possible over our anniversary months. It would be fantastic to see our viewers join in wherever they can - so that our anniversary is not just a wonderful celebration, but also makes a difference."
While the appeal was being planned, the soap's cast were invited to take part in a democratic vote to pick the three charities which would benefit from the project.
All money received through fundraising will be split equally between the charities, however members of the public can also choose to make donations to any of the three organisations directly.
Full details of the Coronation Street 50th Anniversary Appeal and how to donate can be found on the show's official website.