The actress, who plays Sunita Alahan, visited Lesotho where she worked with Riders for Health - an organisation which delivers medical aid and supplies to remote villages only accessible by motorbike.
"It was really tough in the saddle, riding long distances - we covered up to 200km on some days, at altitudes over 7,500m," she told itv.com.
"We were delivering anti-retroviral drugs to people across Lesotho and helping mothers and children in an area where almost one in four are infected with HIV."
She added that she now wants a motorbike of her own.
Gulati was joined by actress Jill Halfpenny, TV host Gethin Jones, cricketer Darren Gough and her Coronation Street co-star Oliver Mellor, who broke his leg on the trip.
The soap star recently took up palm reading as a hobby.