The actress recently filmed her final scenes as the outspoken character, who has recently featured in a love triangle storyline with her friend Audrey Roberts (Sue Nicholls) and cross-dresser Marc Selby (Andrew Hall).
Coronation Street sources have indicated that Claudia's exit paves the way for Audrey and Marc to begin a relationship at last, having formed a firm friendship in recent months.
Lenska told The Mirror of her departure: "I'm hoping they will leave the door open for my return, as I adore Coronation Street so much. I love everyone I work with. I'll be looking forward to doing more theatre when I leave but I hope to return."
Discussing Claudia's disapproval over Marc's cross-dressing, she commented: "I don't think Claudia was very happy when she found out about Marc, but you'll have to wait and see what happens."
Lenska has appeared in Coronation Street on and off since 2009 and Claudia has featured as both a friend and rival for Audrey.
She added: "There's something charming about the Street - what it does with the older generation. It's fantastic that we have so many interesting and fun storylines involving people over 60.
"There are just so many wonderful characters, they can be mischievous and endearing and people love to watch them. That's what they do so well, and what makes it the best soap."
Lenska will go on tour with the stage production of Calendar Girls later this year.
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