Sean is currently absent from Weatherfield as he is looking after his young son Dylan in London. His break from screens reflects the time that Cotton spent away from the UK for his stint on I'm A Celebrity... Get Me Out Of Here and a subsequent holiday.
Cotton has now told Radio Times that Sean will be in for a shock when he returns home - as Eileen Grimshaw's new love interest Paul Kershaw (Tony Hirst) and his wife Lesley (Judy Holt), who suffers from dementia, will be living there.
"[I'm back on screen] in about six weeks," Cotton explained. "I go straight back into the house, where there's somebody else living there. Paul the fireman [and] his wife have moved into the house.
"There's a bit of an explosion when I go back into the house, because I don't know who she is, and she doesn't know who I am. So I go straight back into the thick of things, and I can't wait."
He continued: "Initially, I go back into the house and it all kicks off - because there's lots of people in the house. And there's nothing better on Coronation Street than a house full of people."
Cotton also hinted that Dylan could feature on the show again in a new storyline for Sean and Marcus.
Asked about the youngster, he replied: "There might be something. But I don't know what I can say!"
Coronation Street continues tonight at 7.30pm and 8.30pm on ITV1.
> Read all the latest Coronation Street spoilers and news
Watch a preview of tonight's Coronation Street double bill in the video below: