Audrey, played by Sue Nicholls, has to be rushed to hospital in a fortnight's time after she collapses during another row with her family over the salon.
David (Jack P Shepherd) is devastated over his gran's health scare and immediately regrets their recent feud.
However, tension builds when Kylie refuses to apologise for her part in the battle, leaving David stunned.
Lane told Soaplife: "The fight is pushed right to the back of David's mind and off the agenda, as he's just worried about his gran.
"But Kylie certainly doesn't want to be blamed, because she feels that Audrey's brought much of the stress on herself. She doesn't feel they've added fuel to the fire, but David feels they've pushed it too far."
The situation escalates as Audrey refuses to see a guilty David as she recovers in hospital.
Lane continued: "Kylie hopes Audrey's alright, but she's not sorry. David tries to apologise, but Audrey won't even see him and David takes that hard. Kylie doesn't really understand, and that's when it builds and David starts to resent Kylie."
Coronation Street launches the latest storyline twist on Monday, April 23 at 7.30pm on ITV1.
> Coronation Street Jack P Shepherd: 'I'll defend David over salon war'
> Coronation Street Paula Lane: 'Fans don't recognise me'
> Read more Coronation Street spoilers and news
Watch a preview of Thursday night's (April 12) Coronation Street episode in the video below: