The actress, who plays Maria Connor in the ITV1 soap, is often approached by confused fans who believe her character is real.
"I was in A&E once because I'd cut my eyebrow and was waiting to get it glued together. I was sitting with an ice pack on my head and this woman was trying to talk to me," Ghadie told the Daily Record.
"I thought she was trying to be funny because she was saying, 'I haven't had my hair done for ages, I need to come in and see you'. I thought, 'She obviously thinks I'm Maria'.
"But she didn't. She thought I worked at the hairdressers where she gets her hair done. She'd recognised my face but couldn't place it and just thought I washed her hair or I was the brusher-upper at the hairdresser."
Ghadie, who divorced Matt Smith in November last year and reverted to her maiden name, is still dating former co-star Will Thorp, who played Chris Gray.
Speaking of her character's love life, she added: "Maria never had any success with blokes in the 12 years I've been on the show. Most of them just die on her.
"She's literally the kiss of death for male characters - Tony died, Liam died, Charlie died. Frank died."