The ITV1 soap is due to relocate to Salford Quays next year, but structural issues have now been identified in the steel frame for the new set's base.
Reports in The Mirror and Place North West claim that the frame started to move as concrete was poured onto the site.
ITV has insisted that the issue will only result in a "slight" delay to the new set's progress, while it is also understood that there is no risk of collapse.
A spokesperson for the broadcaster said: "ITV's construction manager, Mace, confirm they are managing a construction issue on the new Coronation Street site, which has resulted in a slight delay to the build.
"Construction of the main building and the Coronation Street lot continues uninterrupted, as does production of the show at the current Quay Street site, and we remain on track to begin ITV's move to the new Media City UK base in the autumn."
Meanwhile, a representative for Mace commented: "Mace confirm that work is in progress to identify the most appropriate strategy to remediate the steel frames of the partially built stage areas of the Coronation Street production facility."
The current Coronation Street set at Quay Street was recently refused listed status by English Heritage.