The Weatherfield actress, who plays Tyrone's violent girlfriend Kirsty Soames, said that she does not initially suspect cruel dad Ed has stolen baby daughter Ruby.
She told ITV.com: "When Ruby goes missing her first reaction is not that it has anything to do with dad.
"Kirsty has been having a nap upstairs and Ruby was sleeping in the pram outside. She is just in a blind panic knocking on doors and desperate to see if anyone has seen or heard anything."
The star further confirmed that the storyline would end with "a lot of anger" and a "fight" between Tyrone (Alan Halsall), Kirsty, Ed and Alison.
Gumede also expressed her gratitude to producers for bringing her parents Ed and Alison - portrayed by David Lonsdale and Dawn Hope - back to the cobbles.
"I am thrilled that Kirsty's parents are back, it gives such an insight into Kirsty. [Alison] is found at the bus stop by Tyrone and he thinks that this may be the answer to the problem," she added.
"To have the mum there helping out eases the pressure on him and the worry. Her mum says that she has left her dad because she can't take the abuse any more and Tyrone suggests that she stays with them to help with the baby.
"But Kirsty is not immediately receptive, she recognises straight away that dad will come looking and that by mum being at the house they are all placed in danger."
The scenes will air in Corrie's double bill next Friday (September 28).
Watch Natalie Gumede's recent Corrie chat with Digital Spy below: