Tabloid reports at the weekend linked O'Brien with a return to the ITV soap as Sarah Platt, having last appeared in 2007.
However, the Waterloo Road actress has taken to Twitter to deny the reports, which originated in the Sunday Mirror.
"So a lot of peeps asking if I'm returning to Corrie but I've only read it in paper like everyone else lol," she wrote.
The report stated that Sarah would return to Weatherfield with her "wild child" daughter Bethany.
A Coronation Street spokesperson told Digital Spy on Sunday (December 30) that new producer Stuart Blackburn doesn't take office until January 7, meaning that any reports about his story plans are just speculation.
O'Brien has recently said that she would be willing to return to the role in the future, stating that a different actress would be "awful".