There will certainly be casualties and may well be fatalities in the blaze, so which Weatherfield resident could be driven to take such drastic action?
Landlady Stella Price and daughters Leanne and Eva will be in the most potential danger, which leads us to believe that the culprit deliberately starts the blaze.
Here, Digital Spy considers the possible suspects for this huge Corrie storyline:
Sunita was recently left heartbroken by Karl's decision to leave her, and with the pressures of bringing up her children, will she be driven to extreme measures if Stella and Karl do the unthinkable and get back together? With actress Michelle Collins recently hinting that the unthinkable might in fact happen, as well as Sunita's tendency for unpredictable behaviour, she has to be a prime suspect. According to tabloid reports, Sunita will publicly turn on Stella a week before the fire starts, meaning locals will suspect she's responsible for the blaze. But, tell me, how many times have Weatherfield's residents been wrong about such things?
Karl Munro has been looking shifty for months, showing his wickedness on a few occasions. His chauvinistic treatment of Sunita, creepy pursuing of Stella and childish pranks directed at Stella's lover Jason mean Karl has to be another prime contender. Without any friends in Weatherfield, it's Karl who certainly has the least to lose by starting the fire. Could another Stella rejection be too much for Karl? But while we've seen his dark side, we've also pondered whether Karl would be so stupid as to start the fire when Stella seems to be gently warming to him.
Yes, it's a rarity that Kirsty has ever spoken to Stella, but could the domestic violence storyline spark the Rovers fire? Kirsty is probably the most psychotic of Corrie's residents and, with the Rovers being Tyrone's local, will Kirsty take drastic measures if Tyrone is found innocent at the trial and wins custody of daughter Ruby, with Kirsty shown to be a liar? It would be an explosive end to a brilliant storyline.
Returning to Weatherfield on Monday, Gloria has been unable to resist a money-making ploy, and perhaps the Rovers represents a chance to win big on insurance. Doubtful though it is that she would put her daughter and granddaughter in danger, it is possible that she's unaware the pair are in the house. As we've realised, many of Gloria's plans have holes - more holes than Joe McIntyre's boat it would appear.
At the start of the month, Lewis left Weatherfield in style after he recorded himself revealing his deception to Gail, but is his work in Weatherfield done? The old smoothy might leave an indelible mark on the cobbles, but it'd be unknown territory for the gigolo. So while we doubt Lewis could be responsible for the Rovers fire, writers might not be able to resist making him evil.
Will it be an accident?
Will Coronation Street bosses stick to tradition and make the fire an accident? Underwhelming, you may feel, but as shown below, the 1986 fire was action-packed, and perhaps the "amazing stunts" promised by Michelle Collins are what the crew are really focusing on.
Who will be the Corrie fire starter? Leave your views below! Get the Inside Soap magazine on your iPhone or iPad