S01E01: 'A Hard Day's Night'

"Grey's Anatomy" follows the lives of first year surgical interns Meredith Grey, Cristina Yang, Izzie Stevens, George O'Malley and Alex Karev at Seattle Grace Hospital, the toughest surgical residency programme west of Harvard. While they were students yesterday, today they're doctors and, in a world where on the job training can be a matter of life and death, they're all juggling the ups and downs of their own personal lives.

The interns are guided by an established team of doctors who are determined to shape them into skilled surgeons or break them: Miranda Bailey, a senior resident responsible for training them, is so tough that she's nicknamed "The Nazi"; Derek Shepherd is the flirtatious but very capable surgeon who shares a forbidden but undeniable sexual attraction with Meredith; and Preston Burke's arrogance is second only to his skill with a scalpel. Overseeing them all is Dr. Richard Webber, Seattle Grace's paternal, but no-nonsense chief of surgery.