S02E06: 'Owner of a Lonely Heart'

Cristina Yang has little sympathy for Constance Ferguson, a prison inmate who jeopardizes her health just to get out of solitary confinement.

Meanwhile, the interns all keep careful watch on the family of premature quintuplets with a variety of serious health challenges.

Izzies anger at Alex reaches boiling point.

And Dr. Addison Shepherd decides to teach Izzie a very painful lesson.