The US firm has said that the initial release will include 13 quad-core processors, mostly for desktop computers, and will be shipping on April 29.
A second wave of dual-core Ivy Bridge processors will follow later in the spring, suitable for Ultrabooks and super-thin laptops.
The 22 nanometre chips feature new transistor technology, involving an on/off switch in the centre of the chip that makes it more power-efficient.
Intel hopes that the Ivy Bridge family will help power a new generation of computers, as well as stimulate sales in the sluggish PC market.
However, the launch is also part of plans to fend off the competition from British firm ARM Holdings, which has built a powerful position in smartphone and tablet chips.
ARM is also threatening Intel's position in the PC market as Microsoft's forthcoming Windows 8 operating system will support ARM-equipped machines.
Intel particularly hopes that new Ivy Bridge chip architecture will help challenge ARM's reputation for energy-efficient technology.
In preparation for the launch, the company has established three factories to build the chips, and a fourth will come online later in the year.
Intel's PC business chief Kirk Skaugen said that Ivy Bridge will get 50% more supply than the last generation of chips, Sandy Bridge, which was released 15 months ago.
"The momentum around the system design is pretty astonishing," Skaugen told the BBC.
"There are more than 300 mobile products in development and more than 270 different desktops, many of which are all-in-one designs.
"This is the world's first 22 nanometre product and we'll be delivering about 20% more processor performance using 20% less average power."
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