The clip-on cases, compatible with iPhone 4 and 4S models, upscale the device's camera to 14-megapixel and enhance its flash capabilities.
Customers who purchase a case will also receive editing software offering filters and integration with software such as Instagram and a profile on the www.i.am network.
"i.am proud to finally launch the i.am+ foto.sosho app and camera to the world from London. Our product fuses fashion with technology, changing the way you look at a smart phone…the i.am+ foto.sosho camera will make your smart phone brilliant," said will.i.am.
The cases will start at £199 for the i.am+ C4 Modern Look edition, while the white V4 edition comes with a QWERTY keyword and a steeper price tag of £299.
i.am+ cases for Apple's latest smartphone, the iPhone 5, are listed as "coming soon".
The i.am+ range will go on sale exclusively through Selfridges from December 6.