The nine-episode series, which aired on NBC last year, stars Slater as a man with two independent personalities. One is a happily married man with an ordinary life, while the other is a secret operative who undertakes 007-style missions.
Sci Fi's pickup of the series follows its recent acquisitions of Joss Whedon's Dollhouse and the remake of Knight Rider.
"We've been investing in a range of compelling, highly-publicised and long-anticipated content to engage, captivate and re-ignite excitement amongst British television viewers," said Jon Farrar, programming director for NBCU Global Networks in the UK. "My Own Worst Enemy absolutely meets this criteria; it's a superior thriller, driven by an outstanding cast, high production values and superb scripts that are punctuated by intrigue, action and extraordinary plot-twists."
My Own Worst Enemy will premiere on Sci Fi in June.