The 30-year-old comic, who quit Never Mind The Buzzcocks last year, makes his writing and acting debut tonight at 10pm on BBC Two.
He told What's On TV: "I guess some people will like it. But I think a lot of people won't be keen on it. It wasn't made with anyone in mind. We made it because we thought it was interesting and funny.
"I don't know really. If it doesn't go well I might have to leave the country! My mum's seen it and she seems to like it, but she likes me being on television!"
Describing the show, Amstell continued: "It's inspired by elements of various people I know. It's written in such a way we want people to ask the question, 'How much of this is real?' And it's not a question I'm interested in resolving.
"I don't know where to draw from other than myself and my issues. It's a version of me - it's all the worst bits of me."
He concluded: "I'm too judgmental, too anxious, too desperate to fix the world, fix this family, unable to let things be. I'm a control freak, narcissistic, claustrophobic, I'm quite snobby, lonely and self-deprecating!
"All the plots are completely invented narratives. I was constantly being told that truth comes from character rather than plot. Although I did moon my grandmother when I was a teenager, which is mentioned in an episode."
> Simon Amstell 'terrified about acting'