The programme, which will air in March to coincide with the 2011 census, focuses on two generations of a family living in a house in Manchester.
Waterloo Road star Eva Pope has signed up to appear in the series along with Jam And Jerusalem's Maggie Steed, Shameless actor Jack Deam and Moses Jones's Wunmi Mosaku.
The show will centre on one generation in 1931 and another in 2011 and will examine how the characters deal with similar issues. Each episode in the five-part series will cover 24 hours and topics included are expected to include pregnancy, addiction, infidelity, mental health and ageing.
Meanwhile, a mystery involving a human bundle buried behind an attic wall in 1931 will run throughout the series.
The show's cast also includes Ciaran McMenamin, David Ross, Rebecca Callard, Tim Dantay, Joe Dixon and Steve Jackson.
BBC Daytime controller Liam Keelan said: "This new warm, accessible, compelling story about a family across the generations, with another high calibre cast, is part of BBC Daytime's ongoing commitment to produce more quality original British drama, which we know our audiences love."
The show is currently being filmed in Manchester.