West, who previously starred in The Wire, will play the infamous serial killer Fred West in the ITV show.
Speaking to The Daily Telegraph, he said: "I am reading up on it and it is disturbing stuff."
West added that the drama may have a big effect on the families and friends of West's victims.
"I imagine they are concerned," he said. "It is a moral minefield. I think it is legitimate to do the film, but if you are related to a victim you can't create that distance. It is very difficult, but as an actor it is such a fantastic opportunity."