The Channel 4 show, described as "a hybrid of The Twilight Zone and Tales of the Unexpected", will focus on the way that technology has changed people's lives.
Brooker will write the first two instalments of the three-part run, while the final episode will be scripted by Peep Show co-creator Jesse Armstrong.
Casino Royale's Rory Kinnear and Rome's Lindsay Duncan will star in premiere episode 'The National Anthem', in which the modern information age creates a huge dilemma for the prime minister.
Second episode '15 Million Merits' - starring Julia Davis, Rupert Everett, Daniel Kaluuya and Jessica Brown-Findlay - will satirise entertainment shows.
The hour-long instalment will portray a future world in which the only way to escape a life of physical labour is to impress judges on the 'Hot Shot' talent show.
Armstrong's contribution, which bears the working title of 'In Memoriam', is set in an alternate reality where all human actions are recorded to a computer system, granting everyone on Earth the power of perfect recall.
Black Mirror has been produced by Zeppotron and is expected to air in late 2011.
> Read Digital Spy's interview with Charlie Brooker