Comedian Dan Renton Skinner's alter ego will take top billing in the newly-commissioned format, which has been announced less than 48 hours after the BBC axed Bob Mortimer and Vic Reeves' long-running panel programme.
Channel 4 revealed that The Angelos Neil Epithemiou Show will feature celebrity guests, new comedy characters and "a full menu of slapstick, jokes, high energy dancing, catchy singing and sophisticated magic".
Mortimer will also cross over from the BBC to serve as executive producer on the new programme.
"We're thrilled we've got the privilege of allowing Mr Angelos Epithemiou to develop his career on Channel 4," comedy editor Fiona McDermott stated.
Epithemiou first appeared on Shooting Stars in 2009 as a permanent panelist for the show's sixth series. He was appointed score keeper the following series when Matt Lucas quit his role as George Dawes.
A one-off version of the show aired earlier this year as part of Channel 4's Comedy Showcase strand.
Watch Dan Renton Skinner in character as Angelos Epithemiou on Shooting Stars below: