The contenders for this year's event have been whittled down by public vote from a longlist released back in September.
Downtown Abbey scores its first NTAs nomination in the 'Drama' category, going up against BBC shows Doctor Who, Merlin and defending champion Waterloo Road.
Also debuting on the shortlist are The Only Way Is Essex and Celebrity Juice, with TOWIE competing against I'm a Celebrity...Get Me Out of Here, Come Dine With Me and The Apprentice to win 'Best Reality Show', and Keith Lemon's quiz landing nominations in the 'Best Panel Game' and 'Entertainment Presenter' categories.
QI, Mock the Week and Have I Got News for You are the other programmes in the running for the 'Panel Game' gong, while Leigh Francis's alter ego will face off against NTAs host Dermot O'Leary, Ant & Dec and Michael McIntyre in the latter category.
Elsewhere, The X Factor, Strictly Come Dancing, Dancing on Ice and Britain's Got Talent will fight it out for 'Best Reality Show', as Michael McIntyre's Comedy Roadshow, Dynamo, Harry Hill's TV Burp and Take Me Out face off in the 'Entertainment Programme' group.
In the acting categories, Doctor Who lead Matt Smith, Torchwood's John Barrowman, Shameless favourite David Threlfall and Doc Martin star Martin Clunes compete for 'Best Male Drama Performance'.
Departing Doctor Who actress Karen Gillan, Torchwood star Eve Myles, Waterloo Road's Jaye Jacobs and Scott & Bailey star Suranne Jones are in line for the 'Female Drama Performance' category.
Coronation Street's Katherine Kelly (Becky McDonald) and Alison King (Carla Connor), Emmerdale actor Danny Miller (Aaron Livesy) and EastEnders star Jessie Wallace (Kat Moon) are up for 'Best Serial Drama Performance'.
Meanwhile, Coronation Street's Chris Fountain (Tommy Duckworth), Emmerdale's Chelsea Halfpenny (Amy Wyatt) and EastEnders actress Jacqueline Joss (Lauren Branning) score nominations in the 'Best Newcomer' category.
The National Television Awards will broadcast live from London's O2 Arena on ITV on January 25.
Fans will be able to choose the winners in each category on the National Television Awards website at nationaltvawards.com. New votes will be added to those submitted earlier in the first round of voting.
> National Television Awards 2012: Nominations shortlist in full
Watch Dermot O'Leary launching this year's awards below: