V Sign will follow a group of human survivors fighting off the universe's most incompetent alien invasion force.
Written by Steve Turner, the pilot will be shot and produced in Northern Ireland, with casting currently ongoing, according to Broadcast.
"I'm delighted that we're getting a chance to show the class of Northern Ireland talent on screen and off," said Jon Rolph, managing director of production company Retort.
"A global alien invasion isn't usually the best way to start a collaboration, but we hope that V Sign's hapless visitors will spearhead many more projects to come from Green Inc and Retort."
Green Inc's Stephen Stewart added: "We have several projects in development with Retort, and are very excited that our first successful project is V Sign.
"Steve Turner's script and the world he has created excited us the first time we read it."
Retort currently produces E4's PhoneShop and The IT Crowd, while Green Inc makes Ask Rhod Gilbert for BBC One.
Ed Tracy (Fonejacker) will direct the V Sign pilot, with Simon Lupton (White Van Man) acting as series producer.
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