Since he began his TV career on Mock the Week, Boyle has thrived and made a living off near-the-knuckle humour. He left the BBC Two show in 2009, complaining about the restrictions that the Beeb placed on him, and found a new home on Channel 4.
Boyle's output on Channel 4 has garnered what we will politely describe as a mixed response. His first series Frankie Boyle's Tramadol Nights (originally titled Deal With This, Retards) failed to capture the public's affection in the way his savage one-liners had done on MTW.
Despite having one critically mauled series, a large number of complaints about gags concerning Katie Price's disabled son Harvey, and an aborted pilot for talkshow Frankie Boyle's Rehabilitation Programme, Channel 4 stood behind Boyle.
His latest project The Boyle Variety Performance launched this month as part of the broadcaster's Funny Fortnight 30th birthday celebrations. However, any chance of the show being spun into a regular series now appears to be in doubt.
Boyle has become a regular fixture on Twitter over recent months with his penchant for twisted quickfire gags well-suited to the 140-character limited social networking site, posting jokes about the latest breaking news and telly trash like Celebrity Big Brother.
But his decision to crack some gags during the Paralympics Opening Ceremony on Wednesday night may just have stepped over Channel 4's line about what's acceptable from its talent. If you believe the press and "insider sources" the broadcaster has washed its hands of the comic.
His jokes were not Boyle's most tasteless or vicious by some margin and were par for the course if you follow his account. But many considered them to be gags at the expense of adults with disabilities and many believe that a taboo too far.
Would it be wrong of Channel 4 to work with Boyle again? Do you believe the broadcaster would be right to dismiss plans for future shows with the comic, because he is willing to poke fun at a national event that the channel has been a passionate cheerleader for?
Or do you think Frankie should be free to make jokes about what he pleases? Channel 4 has caused offence with its comics in the past (Chris Morris's Brass Eye enraged many) - why is this any different? Do we not enter into dangerous territory when we censor what people can or can't make jokes about?
Boyle has taken to Twitter today to hit back at his critics, pointing out that he made similar gags during the Olympic Games and that he doesn't believe he should give the Paralympics special treatment or exception from his skewerings.
And is the biggest problem that some of Boyle's jokes aren't very good, rather than them being beyond the pale? Is it a case of unfunny, rather than unacceptable?
Share your opinion on Frankie Boyle below. Did he go too far or should Channel 4 make more shows with him?