Some 3.53m (a 22.6% share) as well as 170k on +1 watched Friday's edition of the popular quiz game, giving ITV its best ratings in the teatime slot for seven years since Paul O'Grady moved his show to Channel 4.
BBC One's Pointless, meanwhile, could only gather 2.65m (16.1%) between 5.15pm and 6pm for its last classic edition of the year. Pointless Celebrities will air in its place from Monday.
In September, the pair were neck-and-neck but The Chase has not lost to its gameshow rival since October.
Later in the evening, David Mitchell's fifth stint in the Have I Got News For You hosting chair was seen by 4.41m (19.2%) on BBC One at 9pm, then John Bishop's Big Year amused 3.64m (16.3%). Nearly as many, 3.51m (22.7%), stayed up for The Graham Norton Show at 10.35pm.
Meanwhile, ITV1's documentary celebrating 100 Years of the Royal Variety Performance interested 2.94m (13.4%) between 9pm and 10.30pm (+1: 132k). This year's ceremony pulled in a peak of over 9m on Monday.
Channel 4's comedy night kicked off with a showing of Peter Kay: In Conversation which attracted 1.9m (8.4%) from 9pm (+1: 350k), after which 1.29m (8.4%) caught Alan Carr: Chatty Man at 10pm (+1: 301k).
Elsewhere in a fairly competitive 9pm slot, BBC Two documentary Westminster Abbey intrigued 2.28m (10.1%), US drama The Mentalist anchored Channel 5's schedule with 1.18m (5.2%) and An Idiot Abroad maintained 890k (3.9%) on Sky1.
Bolstered by its 90 minutes of soaps, ITV1 topped primetime with 21.5% (+1: 0.5%), beating BBC One's 19.6%. BBC Two slipped into third place with 7.3% ahead of Channel 4's 5.4% (+1: 0.9%) and Channel 5's 3.6% (+1: 0.2%).
BARB ratings data supplied by Attentional