The comedy, which sees some of history's most famous women psychoanalysed by a therapist, originally aired as a one-off episode as part of Playhouse Presents....
The new series, starring Rebecca Front as the therapist, will air in 2013, produced by Tiger Aspect Productions.
Julia Davis will appear as Sylvia Plath, Sharon Horgan as Eve, Sam Spiro as Audrey Hepburn, Frances Barber as Bette Davis, Kathy Burke as Mona Lisa and Katy Brand as Mary Shelley.
Psychobitches will also feature Tamsin Egerton, Selina Griffiths, Zawe Ashton, Jo Scanlan, Sarah Solemani and Sharon D Clarke.
The series will include characters from Jack Whitehall, Harry Enfield and the League of Gentlemen team Mark Gatiss, Reece Shearsmith and Steve Pemberton.
Jeremy Dyson will direct the series and lead the team of writers.
Lucy Lumsden, Head of Comedy at Sky, said: "We are very proud of Psychobitches, a honeypot for our funniest comedy actresses. A treat for 2013."
James Hunt, Channel Director of Sky Arts, has also announced that a new run of Playhouse Presents... will begin in the spring, details of which will be confirmed in January.
Matt Smith, Idris Elba and Marc Warren will feature in episodes of the upcoming run.