The entertainment show, which features celebs imitating classic dance routines, returns on February 16 for a four-week run.
[Let's Dance 2012 winner Rowland Rivron]
Alex Jones and Steve Jones will host the series again and the show will feature a special musical guest every week.
"I'm ridiculously excited to be back on Let's Dance," said Alex Jones. "We have some of our best comedians as panelists, and an unbelievable lineup of brave celebrities who are all prepared to don their dancing shoes to raise lots of money for this year's Red Nose Day.
[2013 'Let's Dance' celebs - Tim Vine and Ricky Hatton]
"Earlier this year Steve and I went out to Malawi to visit a number of projects funded by Comic Relief, and we can't wait to get stuck in, knowing that the money raised this Red Nose Day will go towards helping families in Africa and in the UK that desperately need it."
Steve Jones added: "It's still the most fun I have on TV, so I am ecstatic Let's Dance is back with a whole host of famous faces along with famous arms, legs, necks and fingers all attempting to dance for our viewing pleasure!"
[Former 'Let's Dance' winners Rufus Hound and Charlie Baker & James Thornton]
Previous winners of the show have included Robert Webb dancing to 'Flashdance', Rufus Hound imitating Cheryl Cole, James Thornton and Charlie Baker dancing like Fred Astaire and Rowland Rivron performing to the Fat Boy Slim track 'Weapon of Choice'.
Watch Rowland Rivron's winning performance on Let's Dance for Sport Relief: